Simplificando tratamiento, ganando en funcionalidad

Q4 Medicine Psiquiatria Biologica Pub Date : 2024-12-01 Epub Date: 2024-12-09 DOI:10.1016/j.psiq.2024.100559
Agustín Sánchez Gayango, Paula Cañizares Moreno, Emilio José López Sánchez
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引用次数: 0

Abstract

It is presented the case of a 50-year-old woman referred to a private psychiatrist for schizoaffective disorder of years of evolution, without psychopathological decompensation requiring hospital admission. She reports clinical stability with prescribed treatment: haloperidol 10 mg, risperidone 3 mg, olanzapine 5 mg, biperiden 2 mg, amitriptyline 75 mg and bromazepam 1.5 mg. Gradual treatment changes are proposed in order to simplify the treatment since three different antipsychotics are prescribed without having reached the maximum dose of any of them. These changes require one year to reach antipsychotic monotherapy and then other months to achieve the transition from oral risperidone to monthly injectable and then quarterly. After these changes, the patient expresses improvement of functionality in daily life, which was diminished as a consequence of the side effects of the previous treatment. Although the introduction of escitalopram and clotiapine was necessary due to affective changes when the treatment with paliperidone palmitate monotherapy was started, the current treatment is more simplified than the initial one, maintaining the patient's improvement in functionality and the absence of significant side effects.
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简化治疗,增强功能
它提出的情况下,一个50岁的妇女转介到私人精神科医生的分裂情感障碍多年的进化,没有精神病理失代偿需要住院。她报告了处方治疗的临床稳定性:氟哌啶醇10 毫克,利培酮3 毫克,奥氮平5 毫克,双哌啶酮2 毫克,阿米替林75 毫克,溴西泮1.5 毫克。由于三种不同的抗精神病药物在没有达到其中任何一种的最大剂量的情况下被开处方,因此建议逐步改变治疗以简化治疗。这些变化需要一年的时间才能达到抗精神病药物单一治疗,然后需要其他几个月的时间才能从口服利培酮过渡到每月注射,然后是每季度注射一次。在这些改变之后,患者在日常生活中表现出功能的改善,这是由于先前治疗的副作用而减少的。虽然在开始棕榈酸帕利哌酮单药治疗时,由于情感变化需要引入艾司西酞普兰和氯硫平,但目前的治疗比最初的治疗更简化,保持了患者功能的改善,没有明显的副作用。
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来源期刊
Psiquiatria Biologica
Psiquiatria Biologica Medicine-Psychiatry and Mental Health
CiteScore
0.40
自引率
0.00%
发文量
13
期刊介绍: Es la Publicación Oficial de la Sociedad Española de Psiquiatría Biológica. Los recientes avances en el conocimiento de la bioquímica y de la fisiología cerebrales y el progreso en general en el campo de las neurociencias han abierto el camino al desarrollo de la psiquiatría biológica, fundada sobre bases anatomofisiológicas, más sólidas y científicas que la psiquiatría tradicional.
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