Diabetes and Anemia Prognosis by 2-D Photonic Crystal Biosensor

IF 1.7 4区 物理与天体物理 Q2 PHYSICS, MULTIDISCIPLINARY Brazilian Journal of Physics Pub Date : 2025-01-30 DOI:10.1007/s13538-025-01707-y
Esmat Rafiee
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Abstract

In the presented research, a 2-D optical structure made of photonic crystals is presented. It is based on 30*28 arrays of silicon in medium made of air. Designed system is made of linear media (no nonlinear rods) for overcoming nonlinearity and gain problems. Applicability of designed system can be studied through extracting photonic band gap and field distribution spectra. Latter diagrams would be obtained by utilizing PWE and FDTD techniques. After applying incident light wave, signal can be propagated along the waveguide reaching outputs 1 or 2 according to the resonant wavelengths. Output1 can be considered for diagnosis of glucose levels in blood with Quality factor (Q): (122.72 – 132.5), Sensitivity (S): 1730 nm/RIU, detection limit (DL): (7.01e-4 – 7.15e-4) RIU and Figure of merit (FOM): (134.4 –142.5) RIU−1. In another case, output2 can be considered for diagnosis of hemoglobin levels in blood with (Q): (106.56 – 112.8), (S): 1154.6 nm/RIU, (DL): (1.1e-3 – 1.2e-3) RIU, (FOM): (84.8–87.5) RIU−1. As a result, designed structure would effectively aid researchers in prognosis of diabetes (Output1) and anemia (Output2). Diagnosis of anemia and diabetes (fast and with high precision) in a simple and applicable configuration (made of only linear rods) with considerable characteristics (sensitivity, DL, FOM and Q-factor) are the most important features of the proposed device.

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二维光子晶体生物传感器对糖尿病和贫血的预测
在本研究中,提出了一种由光子晶体构成的二维光学结构。它是基于空气介质中30*28个硅阵列。为了克服非线性和增益问题,设计的系统采用线性介质(无非线性棒)。通过提取光子带隙和场分布谱来研究所设计系统的适用性。后一种图将通过利用PWE和FDTD技术获得。施加入射光波后,信号可根据谐振波长沿波导传播,到达输出1或输出2。Output1可用于诊断血液中的葡萄糖水平,质量因子(Q):(122.72 - 132.5),灵敏度(S): 1730 nm/RIU,检测限(DL): (7.01e-4 - 7.15e-4) RIU,优点图(FOM): (134.4 - 142.5) RIU−1。在另一种情况下,output2可用于诊断血液中血红蛋白水平(Q):(106.56 - 112.8), (S): 1154.6 nm/RIU, (DL): (1.1e-3 - 1.2e-3) RIU, (FOM): (84.8-87.5) RIU−1。因此,设计的结构将有效地帮助研究人员对糖尿病(Output1)和贫血(Output2)的预后进行预测。诊断贫血和糖尿病(快速和高精度)在一个简单和适用的配置(仅由线形棒制成)具有相当的特性(灵敏度,DL, FOM和q因子)是该设备最重要的特点。
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来源期刊
Brazilian Journal of Physics
Brazilian Journal of Physics 物理-物理:综合
CiteScore
2.50
自引率
6.20%
发文量
189
审稿时长
6.0 months
期刊介绍: The Brazilian Journal of Physics is a peer-reviewed international journal published by the Brazilian Physical Society (SBF). The journal publishes new and original research results from all areas of physics, obtained in Brazil and from anywhere else in the world. Contents include theoretical, practical and experimental papers as well as high-quality review papers. Submissions should follow the generally accepted structure for journal articles with basic elements: title, abstract, introduction, results, conclusions, and references.
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