A Recent Progress in Biological Activities of 1,3,4-thiadiazole and its Derivatives: A Review.

IF 3.3 4区 医学 Q3 CHEMISTRY, MEDICINAL Current topics in medicinal chemistry Pub Date : 2025-01-01 DOI:10.2174/0115680266344588241127031534
Sarah Chandurwala, Hardha Balachandran, B Gowramma, M Yokkesh, Vishal Pranav, J Vinethmartin, Aryan Jangra, Sowmiya Arun, L Kaviarasan
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Abstract

1,3,4-thiadiazole can be produced in several ways and has a wide range of possible biological uses. As a result, scientists have created novel procedures for producing 1,3,4-thiadiazole derivatives and their use in medicine. Among the activities are Anticancer, anticonvulsant, antimicrobial, antifungal, antiinflammatory, antiHIV, antidiabetic, antitubercular, antifungal, and other properties. We have compiled different biological activities of 1,3,4-thiadazole in this review study. Many researchers may find the material on this page helpful, which could result in the identification of new medicinal species beneficial to society.

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1,3,4-噻二唑及其衍生物生物活性研究进展
1,3,4-噻二唑有多种制备方法,具有广泛的生物用途。因此,科学家们创造了新的方法来生产1,3,4-噻二唑衍生物及其在医学上的应用。其中的活性有抗癌、抗惊厥、抗菌、抗真菌、抗炎、抗艾滋病毒、抗糖尿病、抗结核、抗真菌和其他特性。本文综述了1,3,4-噻唑的不同生物活性。许多研究人员可能会发现本页上的材料很有帮助,这可能导致对社会有益的新药物物种的鉴定。
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来源期刊
CiteScore
6.40
自引率
2.90%
发文量
186
审稿时长
3-8 weeks
期刊介绍: Current Topics in Medicinal Chemistry is a forum for the review of areas of keen and topical interest to medicinal chemists and others in the allied disciplines. Each issue is solely devoted to a specific topic, containing six to nine reviews, which provide the reader a comprehensive survey of that area. A Guest Editor who is an expert in the topic under review, will assemble each issue. The scope of Current Topics in Medicinal Chemistry will cover all areas of medicinal chemistry, including current developments in rational drug design, synthetic chemistry, bioorganic chemistry, high-throughput screening, combinatorial chemistry, compound diversity measurements, drug absorption, drug distribution, metabolism, new and emerging drug targets, natural products, pharmacogenomics, and structure-activity relationships. Medicinal chemistry is a rapidly maturing discipline. The study of how structure and function are related is absolutely essential to understanding the molecular basis of life. Current Topics in Medicinal Chemistry aims to contribute to the growth of scientific knowledge and insight, and facilitate the discovery and development of new therapeutic agents to treat debilitating human disorders. The journal is essential for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important advances.
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