Cerebral amyloid angiopathy revealed by severe renal failure: A case report

Abstract

Sporadic cerebral amyloid angiopathy is a common condition in the elderly, characterised by the accumulation of amyloid Aβ peptide in the walls of small cerebral arteries, leading to intracranial haemorrhage and cognitive impairment. We present the case of a 65-year-old woman admitted for sudden intracranial hypertension and severe renal failure requiring dialysis.

This case illustrates an uncommon presentation of cerebral amyloid angiopathy in a patient with concurrent end-stage renal disease, highlighting the complex interplay between systemic and cerebrovascular pathology. The diagnostic challenge posed by overlapping neurological and uraemic symptoms underscores the importance of multidisciplinary evaluation in such cases.