Recent progress in palladium-catalyzed reduction with organosilanes

Abstract

Reduction of unsaturated compounds using a standard method in laboratories as well as in industry to achieve valuable compounds is very important. The catalytic activity of various types of palladium (Pd) catalysts in the presence of organosilane for the reduction of unsaturated compounds has been proven over the years. As the main goal of the review, we present a comprehensive overview of the application of Pd catalysts in the presence of organosilane compounds for the reduction of organic building blocks such as thio esters, organic halides, acid chlorides, carboxylic acids, olefins, alkynes, ethers, α,β-unsaturated compounds, carbonyl compounds, alcohols, nitroaromatic derivatives, and imine compounds. We present the recent reports on the reduction of unsaturated compounds using the Pd catalyst/silane system. We briefly discuss the general mechanistic roles played by palladium and organosilane in the reduction reactions.