Optimizing the Transport of Organs for Transplantation

IF 4.3 2区 工程技术 Q2 COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS Computers & Operations Research Pub Date : 2025-04-01 Epub Date: 2024-12-23 DOI:10.1016/j.cor.2024.106934
Isaac Balster , Joyce Azevedo Caetano , Glaydston Mattos Ribeiro , Laura Bahiense
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Abstract

As an organ becomes available for transplantation, a recipient must be selected. Usually, donor and recipient are geographically apart. Therefore, the transport of the organ must be planned and executed within the time window imposed by the maximum preservation time of the organ, which can impact recipient selection. The Cold Ischemia Time - CIT, that is the time elapsed between the surgical removal of the organ and its transplantation, must be the minimum possible to improve the transplantation success. In this sense, the air transport becomes the best option and, sometimes, it is the only way to deliver the organ before perishing. The planning of an organ transportation means choosing, among thousands of possible sequences of flights, the option that delivers the organ faster to its destination. This problem can be modeled as a resource constrained shortest path. Given the urgency and importance of this task, which is solved manually in Brazil, we present a labeling algorithm to find the optimal sequence of flights. Computational tests performed on 25 Brazilian real cases showed a reduction, on average, of 37,46% for the CITs and 44,17% for the transport times.
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优化器官移植运输
当一个器官可供移植时,必须选择一个接受者。通常,捐赠者和接受者在地理上是分开的。因此,器官的运输必须在器官最大保存时间所规定的时间窗口内进行计划和执行,这可能会影响受体的选择。冷缺血时间(CIT),即从手术切除器官到移植器官之间的时间,必须尽可能缩短,以提高移植成功率。从这个意义上说,空运成为最好的选择,有时,这是在器官死亡之前运送器官的唯一途径。器官运输的计划意味着在数千种可能的飞行序列中选择能够更快地将器官运送到目的地的选项。这个问题可以建模为资源受限的最短路径。考虑到这项任务的紧迫性和重要性,我们提出了一种标记算法来找到最优的航班序列。对25个巴西实际案例进行的计算测试表明,cit平均减少了37.46%,运输时间减少了44.17%。
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来源期刊
Computers & Operations Research
Computers & Operations Research 工程技术-工程:工业
CiteScore
8.60
自引率
8.70%
发文量
292
审稿时长
8.5 months
期刊介绍: Operations research and computers meet in a large number of scientific fields, many of which are of vital current concern to our troubled society. These include, among others, ecology, transportation, safety, reliability, urban planning, economics, inventory control, investment strategy and logistics (including reverse logistics). Computers & Operations Research provides an international forum for the application of computers and operations research techniques to problems in these and related fields.
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