Cesium Carbonate-Catalyzed Oxidative Cross-Dehydrogenative Thiolation of Phosphonothioates

IF 3.6 2区 化学 Q1 CHEMISTRY, ORGANIC Journal of Organic Chemistry Pub Date : 2025-02-06 DOI:10.1021/acs.joc.4c02718
Hsiu-Te Hung, Rekha Bai, Sung-Hung Lee, Indrajit Karmakar, Chin-Fa Lee
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Abstract

Herein, we report an aerobic oxidative cross-dehydrogenative coupling (CDC) reaction between thiols and phosphonothioates. The reactions were conducted under mild and transition-metal-free conditions in the presence of air. Not only aryl thiols but also alkyl thiols were successfully coupled with phosphonothioates to form the corresponding phosphorodithioates in good to excellent yields.

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碳酸铯催化硫代膦酸盐氧化交叉脱氢硫代化
在此,我们报道了硫醇和硫代膦酸盐之间的有氧氧化交叉脱氢偶联(CDC)反应。反应是在温和和无过渡金属的条件下在空气中进行的。芳基硫醇和烷基硫醇都成功地与硫代膦酸盐偶联,得到了相应的二硫代膦酸盐,收率很高。
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来源期刊
Journal of Organic Chemistry
Journal of Organic Chemistry 化学-有机化学
CiteScore
6.20
自引率
11.10%
发文量
1467
审稿时长
2 months
期刊介绍: Journal of Organic Chemistry welcomes original contributions of fundamental research in all branches of the theory and practice of organic chemistry. In selecting manuscripts for publication, the editors place emphasis on the quality and novelty of the work, as well as the breadth of interest to the organic chemistry community.
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