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IF 3.4 Q1 Health Professions Animal models and experimental medicine Pub Date : 2025-02-05 DOI:10.1002/ame2.12422
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Abstract

The cover image is based on the article ‘Generation of transgenic chicken through ovarian injection’ (DOI: 10.1002/ame2.12514) reported by Jinghua Jiang, Caiying Wang, Xuguang Du, Fei Gao, Sen Wu. The article presents a technique for generating transgenic chickens in a single generation by injecting DNA into immature oocytes. This method holds immense promise for advancing the genetic manipulation capabilities of avian species that lack primordial germ cell (PGC) lines. The research not only showcases the chicken as a pivotal model organism in developmental biology but also underscores the significant value of genetic modification models in chickens.

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封面图片基于蒋景华、王彩颖、杜旭光、高飞、吴森等发表的文章《通过卵巢注射产生转基因鸡》(DOI: 10.1002/ame2.12514)。本文介绍了一种将DNA注射到未成熟卵母细胞中,实现单代转基因鸡的技术。这种方法对于提高缺乏原始生殖细胞(PGC)系的鸟类物种的遗传操作能力具有巨大的希望。该研究不仅显示了鸡在发育生物学中是一个关键的模式生物,而且强调了鸡基因改造模型的重要价值。
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来源期刊
CiteScore
5.50
自引率
0.00%
发文量
0
审稿时长
12 weeks
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