Impact of exercise-based cardiac rehabilitation on cardiopulmonary function and prognosis in ST elevation myocardial infarction after PCI patients in extremely cold regions.

IF 2.3 3区 医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS BMC Cardiovascular Disorders Pub Date : 2025-02-05 DOI:10.1186/s12872-025-04521-1
Shenglong Hou, Li Liu, Jing Yao, Qi Zhao, Wei Feng, Qingqing Liu, Mou Zou, Ruoxi Zhang, Hongtao Yin, Huimin Xian
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Abstract

Purpose: To evaluate the impact of exercise-based cardiac rehabilitation (CR) on the cardiopulmonary function and prognosis in post-percutaneous coronary intervention (PCI) patients with ST elevation myocardial infarction (STEMI) in extremely cold regions of China.

Methods: This retrospective study included 2,162 patients diagnosed with STEMI who were treated at five medical centers in extremely cold regions of China, between January 2020 and December 2023. All included patients underwent emergency coronary angiography and PCI. Based on whether they received exercise-based CR, patients were divided into a CR group and a non-CR group. To adjust for variations in initial risk factors and baseline characteristics between patients who underwent CR or not, we employed the propensity score matching. Each patient was matched in a 1:1 ratio with replacement. Patients who either participated in CR or did not, but could not be adequately matched, were excluded from the study population. Patient information between the two groups was systematically compared in hospital and at follow-up.

Results: The rate of heart failure, re-hospitalization, and ventricular arrhythmia in CR group was significantly lower than that in non-CR group. The left ventricular ejection fraction (LVEF) measured by echocardiography in CR group were significantly higher than those in non-CR group. The cardiopulmonary test indicators for patients in CR group showed significant improvement over one year, including Power, HR, VCO₂, VO₂, VE, VD/VT, PetCO₂, CHO, CO, and SV, all with statistical significance. Multivariate COX regression analysis showed that CR was independently associated with heart failure in follow up.

Conclusion: Exercise-based CR effectively improves the recovery of cardiac function and prognosis in post-PCI patients with STEMI in extremely cold regions of China.

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以运动为基础的心脏康复对极寒地区PCI术后ST段抬高型心肌梗死患者心肺功能及预后的影响
目的:探讨运动心脏康复(CR)对中国极寒地区ST段抬高型心肌梗死(STEMI)患者经皮冠状动脉介入治疗(PCI)后心肺功能及预后的影响。方法:这项回顾性研究包括2162名被诊断为STEMI的患者,他们在2020年1月至2023年12月期间在中国极寒地区的5个医疗中心接受治疗。所有患者均行急诊冠状动脉造影和PCI。根据患者是否接受了基于运动的CR,将患者分为CR组和非CR组。为了调整初始危险因素和基线特征在接受或不接受CR的患者之间的差异,我们采用倾向评分匹配。每个患者按1:1的比例进行置换。参加CR或未参加CR但不能充分匹配的患者被排除在研究人群之外。系统比较两组住院和随访时的患者信息。结果:CR组心衰、再住院率、室性心律失常率均显著低于非CR组。超声心动图测量CR组左室射血分数(LVEF)明显高于非CR组。CR组患者的心肺试验指标Power、HR、VCO₂、VO₂、VE、VD/VT、PetCO₂、CHO、CO、SV在1年内均有显著改善,差异均有统计学意义。多因素COX回归分析显示,随访时CR与心力衰竭独立相关。结论:运动型CR能有效改善中国极寒地区STEMI pci术后患者心功能恢复及预后。
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来源期刊
BMC Cardiovascular Disorders
BMC Cardiovascular Disorders CARDIAC & CARDIOVASCULAR SYSTEMS-
CiteScore
3.50
自引率
0.00%
发文量
480
审稿时长
1 months
期刊介绍: BMC Cardiovascular Disorders is an open access, peer-reviewed journal that considers articles on all aspects of the prevention, diagnosis and management of disorders of the heart and circulatory system, as well as related molecular and cell biology, genetics, pathophysiology, epidemiology, and controlled trials.
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