Xueqiong Liu , Zediao Huang , Junguo Huang , Tao Zhu , Qingpei Liu , Wenjing Wang , Xiaolong Yang
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引用次数: 0
Abstract
A new steroid, eurotether (1), and three new meroterpenoids, tricycloalternarene I (2), tricycloalternarene J (3) and (2R,3S,4aR)-altenuene-2-acetoxy ester B (4), along with six known compounds (5–10) were isolated from a sewage fungus Eurotium sp. XL-0006. Their structures were elucidated based on NMR analysis, electronic circular dichroism (ECD) calculations and single crystal X-ray diffraction experiments. Compound 1 was the first example of steroid combined with a dibenzo-α-pyrone through double oxygen bridges, and compounds 1–10 were first discovered from Eurotium genus. Compounds 1–6 were evaluated for antibacterial activities against eight clinical drug-resistant bacteria using the microbroth dilution method.
期刊介绍：
Fitoterapia is a Journal dedicated to medicinal plants and to bioactive natural products of plant origin. It publishes original contributions in seven major areas:
1. Characterization of active ingredients of medicinal plants
2. Development of standardization method for bioactive plant extracts and natural products
3. Identification of bioactivity in plant extracts
4. Identification of targets and mechanism of activity of plant extracts
5. Production and genomic characterization of medicinal plants biomass
6. Chemistry and biochemistry of bioactive natural products of plant origin
7. Critical reviews of the historical, clinical and legal status of medicinal plants, and accounts on topical issues.
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