{"title":"Zinc(II)‐Enhanced Excimer Probe for Recognition of MDMB‐CA Synthetic Cannabinoids","authors":"Yihang Wang, Jiahao Dong, Yuan Liu, Longlong Liang, Yuwan Du, Xincun Dou","doi":"10.1002/anie.202423576","DOIUrl":null,"url":null,"abstract":"Specific recognition with optical responses towards the analytes which are structurally diverse and weak chemical‐active remains a big challenge but is of great significance. Here, a zinc(II) enhanced fluorescent emission probe was developed by conjugated modulating and metal bridging to specifically recognition synthetic cannabinoids (SCs). The transformed luminescence mechanism from excimer emission to fluorescence resonance energy transfer was demonstrated upon the integration of coordination and non‐covalent interactions towards target SCs. As a result, the specific and instant detection of the certain type SCs (MDMB‐CA series) was achieved in complicated sample medium. Hence, we envisage that this work would not only offer a novel recognition strategy for SCs, but also advance the development of the optical sensing probe especially for analyzing the substances with diverse structures and weak chemical‐activity, as well as for fighting against the illicit drugs.","PeriodicalId":125,"journal":{"name":"Angewandte Chemie International Edition","volume":"11 1","pages":""},"PeriodicalIF":16.1000,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Angewandte Chemie International Edition","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1002/anie.202423576","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0
Abstract
Specific recognition with optical responses towards the analytes which are structurally diverse and weak chemical‐active remains a big challenge but is of great significance. Here, a zinc(II) enhanced fluorescent emission probe was developed by conjugated modulating and metal bridging to specifically recognition synthetic cannabinoids (SCs). The transformed luminescence mechanism from excimer emission to fluorescence resonance energy transfer was demonstrated upon the integration of coordination and non‐covalent interactions towards target SCs. As a result, the specific and instant detection of the certain type SCs (MDMB‐CA series) was achieved in complicated sample medium. Hence, we envisage that this work would not only offer a novel recognition strategy for SCs, but also advance the development of the optical sensing probe especially for analyzing the substances with diverse structures and weak chemical‐activity, as well as for fighting against the illicit drugs.
期刊介绍:
Angewandte Chemie, a journal of the German Chemical Society (GDCh), maintains a leading position among scholarly journals in general chemistry with an impressive Impact Factor of 16.6 (2022 Journal Citation Reports, Clarivate, 2023). Published weekly in a reader-friendly format, it features new articles almost every day. Established in 1887, Angewandte Chemie is a prominent chemistry journal, offering a dynamic blend of Review-type articles, Highlights, Communications, and Research Articles on a weekly basis, making it unique in the field.