{"title":"Modeling of a Bioengineered Immunomodulating Microenvironment for Cell Therapy (Adv. Healthcare Mater. 5/2025)","authors":"Simone Capuani, Jocelyn Nikita Campa-Carranza, Nathanael Hernandez, Corrine Ying Xuan Chua, Alessandro Grattoni","doi":"10.1002/adhm.202570028","DOIUrl":null,"url":null,"abstract":"<p><b>Bioengineered Microenvironment Modeling</b></p><p>The cover of article 2304003 by Alessandro Grattoni and co-workers depicts the cross section of a bioengineered subcutaneous vascularized implant for cell encapsulation with local delivery of immunosuppressants. Alongside, a computational model, accounting for cell and vascular density, predicts oxygen and drugs distribution within the microenvironment.\n\n <figure>\n <div><picture>\n <source></source></picture><p></p>\n </div>\n </figure></p>","PeriodicalId":113,"journal":{"name":"Advanced Healthcare Materials","volume":"14 5","pages":""},"PeriodicalIF":9.6000,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/adhm.202570028","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Advanced Healthcare Materials","FirstCategoryId":"5","ListUrlMain":"https://advanced.onlinelibrary.wiley.com/doi/10.1002/adhm.202570028","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ENGINEERING, BIOMEDICAL","Score":null,"Total":0}
引用次数: 0
Abstract
Bioengineered Microenvironment Modeling
The cover of article 2304003 by Alessandro Grattoni and co-workers depicts the cross section of a bioengineered subcutaneous vascularized implant for cell encapsulation with local delivery of immunosuppressants. Alongside, a computational model, accounting for cell and vascular density, predicts oxygen and drugs distribution within the microenvironment.
期刊介绍：
Advanced Healthcare Materials, a distinguished member of the esteemed Advanced portfolio, has been dedicated to disseminating cutting-edge research on materials, devices, and technologies for enhancing human well-being for over ten years. As a comprehensive journal, it encompasses a wide range of disciplines such as biomaterials, biointerfaces, nanomedicine and nanotechnology, tissue engineering, and regenerative medicine.
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