Xiaoya Gu , Zhe Ma , Lin Zhou , Na Li , Shijiang Yu , Fu Wang , Ruifang An
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引用次数: 0
Abstract
Human papillomavirus (HPV) screening is crucial for the diagnosis of cervical cancer. In this study, we have combined photoactivated CRISPR–Cas12a with tube-in-tube structure and recombinase polymerase amplification (RPA) to enable simple, rapid and convenient visualization detection of HPV16, facilitated by blue UV light at 302 nm. It serves as a potential tool for on-site diagnostic use, which could be beneficial in terms of portability and speed.
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