A nitric oxide-boosting molecular agent to enhance mild-temperature photothermal therapy

IF 4.3 2区 化学 Q2 CHEMISTRY, MULTIDISCIPLINARY Chemical Communications Pub Date : 2025-02-19 DOI:10.1039/d5cc00219b
Xinhao Zhang, Wei Pan, Jialin Kuang, Kaiye Wang, Na Li, Bo Tang
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Abstract

A nitric oxide (NO)-boosting molecular agent (CyHU) was developed for enhanced mild-temperature photothermal therapy (MPTT). This photothermal agent can specifically target mitochondria and efficiently produce NO, inhibiting adenosine triphosphate-dependent heat shock proteins, reversing tumor heat tolerance and ultimately achieving MPTT of cancer cells.

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来源期刊
Chemical Communications
Chemical Communications 化学-化学综合
CiteScore
8.60
自引率
4.10%
发文量
2705
审稿时长
1.4 months
期刊介绍: ChemComm (Chemical Communications) is renowned as the fastest publisher of articles providing information on new avenues of research, drawn from all the world''s major areas of chemical research.
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