Indications, Management, and Short- and Medium-Term Outcomes of Patients with Chronic Coronary Occlusion Treated with Percutaneous Revascularization-A Single-Center Study.

IF 2.4 4区医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS Journal of Cardiovascular Development and Disease Pub Date : 2025-02-16 DOI:10.3390/jcdd12020075

Lucia Barbieri, Gabriele Tumminello, Lorenzo Mafrici, Guido Pasero, Luca Mircoli, Federico Colombo, Cecilia Gobbi, Alessandra S Rizzuto, Stefano Carugo

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Abstract

The diagnosis of chronic total occlusion (CTO), characterized by the complete obstruction of a coronary artery for at least three months, remains challenging and can be entirely asymptomatic. Since the indications for performing a recanalization procedure for CTO do not originate from randomized controlled trials, this study aimed to assess the indications, management, and procedural outcomes of patients undergoing percutaneous revascularization (PCI) for a CTO, ensuring that the population was as uniform as possible regarding technologies and methodological approaches. Forty-one consecutive patients who underwent PCI for CTO recanalization were enrolled from January 2021 to 2024. Additional outcomes included mortality, major adverse cardiovascular events, and the presence of residual cardiac symptoms, with a median follow-up of 449 days and an interquartile range of 230-643 days. Our real-life study confirmed that PCI for CTO has a high success rate and a low incidence of major complications.

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