Clinical study on the application effect of improved polyetheretherketone cranial plate in cranioplasty.

IF 1.6 4区 医学 Q4 BIOPHYSICS Biointerphases Pub Date : 2025-01-01 DOI:10.1116/6.0004208
Jiajun Qin, Fei Xue, Jin Fu, Jiping Sun
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Abstract

This study evaluates the clinical outcomes associated with the use of an improved polyetheretherketone (PEEK) cranial plate in cranioplasty surgery. A total of 104 patients were involved, with significant findings revealing a reduced incidence of postoperative adverse reactions in the improved PEEK group (28.85%) compared to the conventional PEEK group (50.00%, P = 0.027). Patient satisfaction rates were markedly higher in the improved PEEK cohort (P < 0.05). Although the medical expenses for the enhanced PEEK group were greater (¥ 144 600 ± 21 200 vs ¥ 127 400 ± 20 100, P < 0.05), there were no notable differences in cerebral blood flow perfusion or survival time between the two groups (P > 0.05). The conclusions indicate that while the enhanced PEEK cranial plates incur higher upfront costs, their benefits in terms of safety and patient satisfaction, along with improved implant stability and bone healing, support their use in clinical practice. Consequently, the upgraded PEEK material is recommended for cranioplasty procedures.

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本研究评估了在开颅手术中使用改良聚醚醚酮(PEEK)颅骨板的临床效果。共有 104 名患者参与了这项研究,研究结果表明,与传统 PEEK 组(50.00%,P = 0.027)相比,改进型 PEEK 组的术后不良反应发生率(28.85%)明显降低。改进型 PEEK 组的患者满意度明显更高(P 0.05)。结论表明,虽然增强型 PEEK 颅骨板的前期成本较高,但其在安全性和患者满意度方面的优势,以及植入物稳定性和骨愈合的改善,支持其在临床实践中的应用。因此,建议在颅骨成形术中使用升级版 PEEK 材料。
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来源期刊
Biointerphases
Biointerphases 生物-材料科学:生物材料
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35
期刊介绍: Biointerphases emphasizes quantitative characterization of biomaterials and biological interfaces. As an interdisciplinary journal, a strong foundation of chemistry, physics, biology, engineering, theory, and/or modelling is incorporated into originated articles, reviews, and opinionated essays. In addition to regular submissions, the journal regularly features In Focus sections, targeted on specific topics and edited by experts in the field. Biointerphases is an international journal with excellence in scientific peer-review. Biointerphases is indexed in PubMed and the Science Citation Index (Clarivate Analytics). Accepted papers appear online immediately after proof processing and are uploaded to key citation sources daily. The journal is based on a mixed subscription and open-access model: Typically, authors can publish without any page charges but if the authors wish to publish open access, they can do so for a modest fee. Topics include: bio-surface modification nano-bio interface protein-surface interactions cell-surface interactions in vivo and in vitro systems biofilms / biofouling biosensors / biodiagnostics bio on a chip coatings interface spectroscopy biotribology / biorheology molecular recognition ambient diagnostic methods interface modelling adhesion phenomena.
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