{"title":"A large field of view 2- and 3-photon microscope","authors":"Jack Waters","doi":"10.1038/s41377-025-01780-7","DOIUrl":null,"url":null,"abstract":"<p>A new multiphoton fluorescence microscope has been developed, offering cellular resolution across a large field of view deep within biological tissues. This opens new possibilities across a range of biological sciences, particularly within neuroscience where optical approaches can reveal signaling in real time throughout an extended network of cells distributed through the brain of an awake, behaving mouse.</p>","PeriodicalId":18069,"journal":{"name":"Light-Science & Applications","volume":"29 1","pages":""},"PeriodicalIF":20.6000,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Light-Science & Applications","FirstCategoryId":"1089","ListUrlMain":"https://doi.org/10.1038/s41377-025-01780-7","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"OPTICS","Score":null,"Total":0}
引用次数: 0
Abstract
A new multiphoton fluorescence microscope has been developed, offering cellular resolution across a large field of view deep within biological tissues. This opens new possibilities across a range of biological sciences, particularly within neuroscience where optical approaches can reveal signaling in real time throughout an extended network of cells distributed through the brain of an awake, behaving mouse.