{"title":"Hydrogen Bond-Controlled Site-Selective C(sp<sup>3</sup>)-H Alkylation of Sulfonanilides.","authors":"Hui Jiang, Kohei Sekine, Yoichiro Kuninobu","doi":"10.1021/acs.joc.5c00027","DOIUrl":null,"url":null,"abstract":"<p><p>We successfully developed a decatungstate-catalyzed benzylic C(sp<sup>3</sup>)-H alkylation of sulfonanilides by utilizing the hydrogen bond between the sulfonamide group of the substrates and decatungstate photocatalysts. Using this catalytic system, site-selective C(sp<sup>3</sup>)-H alkylation was achieved at the benzylic position near the sulfonamide group.</p>","PeriodicalId":57,"journal":{"name":"Journal of Organic Chemistry","volume":" ","pages":"3454-3467"},"PeriodicalIF":3.3000,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Organic Chemistry","FirstCategoryId":"1","ListUrlMain":"https://doi.org/10.1021/acs.joc.5c00027","RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/2/27 0:00:00","PubModel":"Epub","JCR":"Q1","JCRName":"CHEMISTRY, ORGANIC","Score":null,"Total":0}
引用次数: 0
Abstract
We successfully developed a decatungstate-catalyzed benzylic C(sp3)-H alkylation of sulfonanilides by utilizing the hydrogen bond between the sulfonamide group of the substrates and decatungstate photocatalysts. Using this catalytic system, site-selective C(sp3)-H alkylation was achieved at the benzylic position near the sulfonamide group.
期刊介绍：
Journal of Organic Chemistry welcomes original contributions of fundamental research in all branches of the theory and practice of organic chemistry. In selecting manuscripts for publication, the editors place emphasis on the quality and novelty of the work, as well as the breadth of interest to the organic chemistry community.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
