{"title":"Application and advances of multifunctional magnetic nanoparticles in cross-disciplinary research: From design to detection, imaging, and therapy","authors":"Yujie Zhao, Liyi Zhou, Jiali Ren","doi":"10.1016/j.ccr.2025.216590","DOIUrl":null,"url":null,"abstract":"<div><div>In recent years, magnetic nanoparticles (MNPs) have been increasingly used in cross-disciplinary applications, especially biomedicine. Due to their unique physicochemical properties such as superparamagnetism, high specific surface area, biocompatibility, and easy surface modification, they have become a hotspot in biomedical research. MNPs have already made a significant contribution to the fields of magnetic hyperthermia, targeted drug delivery, and magnetic resonance imaging, and they are an important tool for tumor therapy. This work reviews MNPs of structure, types, synthesis, and their applications in cross-disciplinary, focusing on the latest research progress of MNPs in cancer and tumors. In addition, to respond to the ever-changing challenges of medical development and people's pursuit of a healthy life, this work also describes the synergistic therapeutic and antibacterial studies of MNPs. In addition, the prevention and application of MNPs in foodborne diseases. Finally, we summarize the advantages and challenges of MNPs and discuss the potential of MNPs in the biomedical field and future research prospects.</div></div>","PeriodicalId":289,"journal":{"name":"Coordination Chemistry Reviews","volume":"534 ","pages":"Article 216590"},"PeriodicalIF":20.3000,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Coordination Chemistry Reviews","FirstCategoryId":"92","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0010854525001602","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, INORGANIC & NUCLEAR","Score":null,"Total":0}
引用次数: 0
Abstract
In recent years, magnetic nanoparticles (MNPs) have been increasingly used in cross-disciplinary applications, especially biomedicine. Due to their unique physicochemical properties such as superparamagnetism, high specific surface area, biocompatibility, and easy surface modification, they have become a hotspot in biomedical research. MNPs have already made a significant contribution to the fields of magnetic hyperthermia, targeted drug delivery, and magnetic resonance imaging, and they are an important tool for tumor therapy. This work reviews MNPs of structure, types, synthesis, and their applications in cross-disciplinary, focusing on the latest research progress of MNPs in cancer and tumors. In addition, to respond to the ever-changing challenges of medical development and people's pursuit of a healthy life, this work also describes the synergistic therapeutic and antibacterial studies of MNPs. In addition, the prevention and application of MNPs in foodborne diseases. Finally, we summarize the advantages and challenges of MNPs and discuss the potential of MNPs in the biomedical field and future research prospects.
期刊介绍:
Coordination Chemistry Reviews offers rapid publication of review articles on current and significant topics in coordination chemistry, encompassing organometallic, supramolecular, theoretical, and bioinorganic chemistry. It also covers catalysis, materials chemistry, and metal-organic frameworks from a coordination chemistry perspective. Reviews summarize recent developments or discuss specific techniques, welcoming contributions from both established and emerging researchers.
The journal releases special issues on timely subjects, including those featuring contributions from specific regions or conferences. Occasional full-length book articles are also featured. Additionally, special volumes cover annual reviews of main group chemistry, transition metal group chemistry, and organometallic chemistry. These comprehensive reviews are vital resources for those engaged in coordination chemistry, further establishing Coordination Chemistry Reviews as a hub for insightful surveys in inorganic and physical inorganic chemistry.