Endoscopic healing in IBD: Still the target to achieve?

IF 3.8 3区 医学 Q1 GASTROENTEROLOGY & HEPATOLOGY Digestive and Liver Disease Pub Date : 2025-05-01 Epub Date: 2025-03-11 DOI:10.1016/j.dld.2025.02.009
Andrea Buda , Tommaso Pessarelli , Giovanni Aldinio , Manuela De Bona , Marietta Iacucci , Gian Eugenio Tontini
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Abstract

Mucosal healing is the mainstream goal of modern treat-to-target strategy as it is associated with a significantly more favorable disease course in IBD patients with either ulcerative colitis or Crohn's disease.
Recent advances in endoscopic imaging technologies have overcome the traditional concept of mucosal healing assessed with conventional white light imaging, allowing for multiple levels of endoscopic healing up to the boundaries of molecular and functional evaluation.
In this review, we focused on conventional and emerging strategies to assess endoscopic healing in ulcerative colitis and ileocolonic Crohn's disease, examining their pros and cons in real life practice.
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内窥镜治疗IBD:仍然是要实现的目标吗?
粘膜愈合是现代治疗-靶向策略的主流目标,因为它与溃疡性结肠炎或克罗恩病的IBD患者的病程显著更有利相关。内镜成像技术的最新进展已经克服了用传统白光成像评估粘膜愈合的传统概念,允许多级内镜愈合达到分子和功能评估的界限。在这篇综述中,我们重点介绍了评估溃疡性结肠炎和回结肠克罗恩病的内镜愈合的传统策略和新兴策略,并在现实生活中研究了它们的优缺点。
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来源期刊
Digestive and Liver Disease
Digestive and Liver Disease 医学-胃肠肝病学
CiteScore
6.10
自引率
2.20%
发文量
632
审稿时长
19 days
期刊介绍: Digestive and Liver Disease is an international journal of Gastroenterology and Hepatology. It is the official journal of Italian Association for the Study of the Liver (AISF); Italian Association for the Study of the Pancreas (AISP); Italian Association for Digestive Endoscopy (SIED); Italian Association for Hospital Gastroenterologists and Digestive Endoscopists (AIGO); Italian Society of Gastroenterology (SIGE); Italian Society of Pediatric Gastroenterology and Hepatology (SIGENP) and Italian Group for the Study of Inflammatory Bowel Disease (IG-IBD). Digestive and Liver Disease publishes papers on basic and clinical research in the field of gastroenterology and hepatology. Contributions consist of: Original Papers Correspondence to the Editor Editorials, Reviews and Special Articles Progress Reports Image of the Month Congress Proceedings Symposia and Mini-symposia.
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