{"title":"Role of exosomes in regulating ferroptosis of tumor cells.","authors":"Ruixue Xu, Yu Wang","doi":"10.11817/j.issn.1672-7347.2024.230595","DOIUrl":null,"url":null,"abstract":"<p><p>Exosomes are nanoscale extracellular vesicles widely present in various body fluids. They carry a variety of substances, including proteins, lipids, and nucleic acids, and play significant roles in the body by participating in immune regulation, intercellular signal transduction, and the transport of proteins and nucleic acids. Exosomes can regulate tumor development and drug resistance by modulating ferroptosis. Leveraging the delivery capabilities of exosomes to modulate ferroptosis provides new ideas and greater possibilities for clinical anti-tumor therapies.</p>","PeriodicalId":39801,"journal":{"name":"中南大学学报(医学版)","volume":"49 10","pages":"1683-1691"},"PeriodicalIF":0.0000,"publicationDate":"2024-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11897961/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"中南大学学报(医学版)","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.11817/j.issn.1672-7347.2024.230595","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
Abstract
Exosomes are nanoscale extracellular vesicles widely present in various body fluids. They carry a variety of substances, including proteins, lipids, and nucleic acids, and play significant roles in the body by participating in immune regulation, intercellular signal transduction, and the transport of proteins and nucleic acids. Exosomes can regulate tumor development and drug resistance by modulating ferroptosis. Leveraging the delivery capabilities of exosomes to modulate ferroptosis provides new ideas and greater possibilities for clinical anti-tumor therapies.
期刊介绍:
Journal of Central South University (Medical Sciences), founded in 1958, is a comprehensive academic journal of medicine and health sponsored by the Ministry of Education and Central South University. The journal has been included in many important databases and authoritative abstract journals at home and abroad, such as the American Medline, Pubmed and its Index Medicus (IM), the Netherlands Medical Abstracts (EM), the American Chemical Abstracts (CA), the WHO Western Pacific Region Medical Index (WPRIM), and the Chinese Science Citation Database (Core Database) (CSCD); it is a statistical source journal of Chinese scientific and technological papers, a Chinese core journal, and a "double-effect" journal of the Chinese Journal Matrix; it is the "2nd, 3rd, and 4th China University Excellent Science and Technology Journal", "2008 China Excellent Science and Technology Journal", "RCCSE China Authoritative Academic Journal (A+)" and Hunan Province's "Top Ten Science and Technology Journals". The purpose of the journal is to reflect the new achievements, new technologies, and new experiences in medical research, medical treatment, and teaching, report new medical trends at home and abroad, promote academic exchanges, improve academic standards, and promote scientific and technological progress.