{"title":"Advances in clinical neurorestorative treatments in brain trauma","authors":"Qian Zhou , Wei Shen , Liang Wen","doi":"10.1016/j.jnrt.2025.100191","DOIUrl":null,"url":null,"abstract":"<div><div>Traumatic brain injury (TBI) is a significant cause of mortality and disability globally, imposing a considerable burden on society and individuals. In recent years, neurorestorative therapies for TBI have attracted widespread attention. Despite the rapid progress in clinical neurorestorative treatments for TBI, few relevant reviews have been published. This review addresses advances in these strategies for patients with TBI, covering cellular therapies, neurostimulation therapies, brain-computer interfaces, pharmacologic therapies, and multidisciplinary therapies. This review aims to serve as a reference for clinical professionals treating patients with TBI, improving neurologic rehabilitation and outcomes for patients with TBI.</div></div>","PeriodicalId":44709,"journal":{"name":"Journal of Neurorestoratology","volume":"13 3","pages":"Article 100191"},"PeriodicalIF":3.1000,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Neurorestoratology","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2324242625000130","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Traumatic brain injury (TBI) is a significant cause of mortality and disability globally, imposing a considerable burden on society and individuals. In recent years, neurorestorative therapies for TBI have attracted widespread attention. Despite the rapid progress in clinical neurorestorative treatments for TBI, few relevant reviews have been published. This review addresses advances in these strategies for patients with TBI, covering cellular therapies, neurostimulation therapies, brain-computer interfaces, pharmacologic therapies, and multidisciplinary therapies. This review aims to serve as a reference for clinical professionals treating patients with TBI, improving neurologic rehabilitation and outcomes for patients with TBI.