Remodeling of the neutrophil proteome upon exposure to Pseudomonas aeruginosa biofilms.

Abstract

Neutrophils play important roles within the innate immune system as the first line of defense against invading pathogens. Pathogens counteract these defenses through multiple mechanisms, including protective biofilm formation. Herein, we assessed proteome remodeling between Pseudomonas aeruginosa biofilms and HL-60 cells to provide new insights into host defense responses.