A. A. Timoshin, K. B. Shumaev, V. L. Lakomkin, A. A. Abramov, E. K. Ruuge
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引用次数: 0
Abstract
The aim of the work was to study the effect of dinitrosyl iron complexes (DNIC) with a ligand based on N-acetyl-L-cysteine upon its prolonged administration into the rat body by inhalation. It was found that as a result of this, an effective transfer of stabilized forms of NO occurred through the alveolar wall into the lung tissue. Accumulation of dinitrosyl iron complexes with protein ligands in the lungs and other organs, an increase in their total NO level, as well as a significant and prolonged hypotensive effect were observed.
BiophysicsBiochemistry, Genetics and Molecular Biology-Biophysics
CiteScore
1.20
自引率
0.00%
发文量
67
期刊介绍：
Biophysics is a multidisciplinary international peer reviewed journal that covers a wide scope of problems related to the main physical mechanisms of processes taking place at different organization levels in biosystems. It includes structure and dynamics of macromolecules, cells and tissues; the influence of environment; energy transformation and transfer; thermodynamics; biological motility; population dynamics and cell differentiation modeling; biomechanics and tissue rheology; nonlinear phenomena, mathematical and cybernetics modeling of complex systems; and computational biology. The journal publishes short communications devoted and review articles.
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