Organized Breast Cancer Screening in Diabetic Women: A Prospective Study Among 100,000 Women from the Grand-Est Region (France), from 2020 to 2022.

Abstract

Objective: The risk of breast cancer in type 2 diabetic women is increased by 10-20%. Diabetic women have a higher risk of being diagnosed with advanced breast cancer and having complications with its treatments. In France, women aged between 50 and 74 years old are invited to undergo organized breast cancer screening (OBCS). The objective of this study was to evaluate OBCS participation in a large cohort of diabetic women.

Materials and methods: Based on data from Social Security reimbursement databases, we studied OBCS participation rate of 50-74 years old diabetic women from the Grand-Est region (France) between 2020 and 2022, according to four age brackets and their geographical areas.

Results: In 2020, among the 99,302 diabetic women, 16,340 (16.45%) underwent OBCS versus 24% in the general population. In 2021, among the 100,390 diabetic women, 20,914 (20.83%) underwent OBCS, versus 29% in the general population. In 2022, among the 101,694 diabetic women, 18,576 (18.27%) underwent OBCS, versus 24% in the general population. OBCS participation in 50-54 years old and 70-74 years olds were significantly lower (p<0.0001 in 2020; p<0.0001 in 2021; p<0.0037 in 2022). There was a significant link between OBSC participation and geographical area (p<0.0001).

Conclusion: The OBCS participation rate in women with type 2 diabetes was significantly lower than the general population, and associated with age and area. These findings suggest a need to inform patients and health care professionals about the higher risk of breast cancer in diabetic women to improve OBCS rates with the proven associated health benefits.