A Case of Seborrheic Keratosis in an Adolescent: Quite Rare Disease in Japan.

Q3 Medicine Tokai Journal of Experimental and Clinical Medicine Pub Date : 2025-04-20
Tomomichi Shimizu, Fumikazu Yamazaki, Hanako Yamaoka, Akio Kondoh, Masayuki Kato, Tomotaka Mabuchi
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Abstract

A 19-year-old woman with three seborrheic keratosis on her right abdomen and five seborrheic keratosis on her both buttocks is presented. That developed at the age of five and two months prior to the visit. At our initial dermatological examination, we noticed three oval, well defined, brown tumors on her right abdomen, and several round, well defined, brown nodules on her both buttocks. Dermoscopy findings showed comedo-like openings, fissures, and ridges. Histopathological examination showed hyperkeratosis and pseudohorn cysts, and basaloid keratinocytes proliferation with no dysplastic cells. These findings were consistent with SK. She was treated by cryotherapy using a liquid nitrogen spray, and her tumors and nodules dropped off entirely. Juvenile-onset of seborrheic keratosis is quite rare in East Asian countries and needs to be differentiated from keratinocytic epidermal nevus.

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1例青少年脂溢性角化病:在日本相当罕见的疾病。
一位19岁的女性,右腹部有三处脂溢性角化病,双臀有五处脂溢性角化病。这是在5岁零2个月前出现的。在最初的皮肤检查中,我们发现在她的右腹部有三个椭圆形、清晰的棕色肿瘤,在她的两个臀部有几个圆形、清晰的棕色结节。皮肤镜检查结果显示粉刺样的开口、裂隙和隆起。组织病理学检查显示角化过度和假角囊肿,基底样角化细胞增生,未见发育异常细胞。这些发现与SK一致。她接受了液氮喷雾冷冻治疗,肿瘤和结节完全消失。少年型脂溢性角化病在东亚国家相当罕见,需要与角化细胞性表皮痣鉴别。
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来源期刊
CiteScore
1.10
自引率
0.00%
发文量
32
期刊介绍: The Tokai Journal of Experimental and Clinical Medicine, also referred to as Tokai Journal, is an official quarterly publication of the Tokai Medical Association. Tokai Journal publishes original articles that deal with issues of clinical, experimental, socioeconomic, cultural and/or historical importance to medical science and related fields. Manuscripts may be submitted as full-length Original Articles or Brief Communications. Tokai Journal also publishes reviews and symposium proceedings. Articles accepted for publication in Tokai Journal cannot be reproduced elsewhere without written permission from the Tokai Medical Association. In addition, Tokai Journal will not be held responsible for the opinions of the authors expressed in the published articles.
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