Phytosomes as a New Frontier and Emerging Nanotechnology Platform for Phytopharmaceuticals: Therapeutic and Clinical Applications.

Abstract

A complete investigation into phytosome-based formulations and innovative nanotechnology is presented in this review. This investigation aims to improve the bioavailability and therapeutic effectiveness of herbal components. Phytosomes can significantly increase solubility, absorption, and stability compared to standard herbal formulations by encapsulating active phytoconstituents into phospholipid complexes. This unique ability of phytosomes to overcome the limits of traditional herbal formulations is a potential game changer in medicine. This study highlights the different uses of phytosomes across various health disorders, such as neurodegenerative illnesses, inflammatory conditions, diabetes, cardiovascular diseases, and wound healing. The review also discusses the potential of phytosomes in treating infectious diseases by improving the delivery of bioactive compounds that have improved anticancer efficacy and antibacterial properties. Despite the emergence of numerous groundbreaking discoveries, substantial barriers remain that hinder their widespread application. Challenges that must be addressed include stability, large-scale manufacture, regulatory hurdles, and limited clinical translation. This review also examines the limitations present in clinical practice, mainly focusing on the variability in bioavailability. The review highlights the crucial need for future research in phytosomes, engaging the researchers and emphasizing the continuous evolution of this promising area of medicine.