Efficacy of psychological interventions on sleep in children and adolescents with chronic pain: a systematic review with meta-analysis of randomized controlled trials.
Tanya L Thwaite, Emma A Craige, Niamh Mundell, Daniel L Belavy, Scott D Tagliaferri, Kate Vincent, Sally A Ferguson, Madeline Sprajcer, Patrick J Owen, Grace E Vincent
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引用次数: 0
Abstract
Study objectives: Chronic pain and comorbid sleep difficulties impact many children and adolescents. This study aimed to evaluate the efficacy of psychological interventions on sleep in children and adolescents with chronic pain.
Methods: Five databases (PubMed, CINAHL, APA PsychInfo, Embase, CENTRAL) were searched from inception to April 17, 2023, for randomized controlled trials examining the effects of psychological interventions on sleep in participants aged ≤ 19 years with pain persisting for ≥ 12 weeks. Six studies (participants, n = 686; 78.43% female) were included. Cochrane Risk-of-Bias 2 and GRADE (Grading of Recommendations, Assessment, Development and Evaluation) criteria were employed.
Results: Pairwise random-effects restricted maximum likelihood meta-analysis demonstrated no effect of psychological interventions on sleep (g [95% confidence interval]: -0.04 [-0.19, 0.11], P = .613, GRADE: high), pain intensity (0.05 [-0.17, 0.27], P = .563, GRADE: high), depressive symptomatology (0.17 [-0.27, 0.62], P = .304, GRADE: moderate), or anxious symptomatology (g: 0.13 [-0.32, 0.57], P = .351, GRADE: moderate). Subjective outcomes may limit clinical utility, and risk of bias (some concern for all studies) decreased confidence in effect estimates.
Conclusions: Development and evaluation of psychological interventions specifically tailored to address comorbidities of sleep difficulties in child and adolescent chronic pain populations is warranted.
Systematic review registration: Registry: PROSPERO; Name: Efficacy of Psychological Interventions for Sleep in Children and Adolescents with Chronic Pain: A Systematic Review and Meta-Analysis of Randomised Controlled Trials; URL: https://www.crd.york.ac.uk/PROSPERO/view/CRD42023454620; Identifier: CRD42023454620.
Citation: Thwaite TL, Craige EA, Mundell N, et al. Efficacy of psychological interventions on sleep in children and adolescents with chronic pain: a systematic review with meta-analysis of randomized controlled trials. J Clin Sleep Med. 2025;21(8):1445-1461.
期刊介绍：
Journal of Clinical Sleep Medicine focuses on clinical sleep medicine. Its emphasis is publication of papers with direct applicability and/or relevance to the clinical practice of sleep medicine. This includes clinical trials, clinical reviews, clinical commentary and debate, medical economic/practice perspectives, case series and novel/interesting case reports. In addition, the journal will publish proceedings from conferences, workshops and symposia sponsored by the American Academy of Sleep Medicine or other organizations related to improving the practice of sleep medicine.
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