Exploring Manufacturing Techniques in Bioceramic Scaffold Fabrication with a Focus on DIW 3D Printing for Tissue Engineering Applications

IF 5.4 2区 医学 Q3 ENGINEERING, BIOMEDICAL Annals of Biomedical Engineering Pub Date : 2025-04-03 DOI:10.1007/s10439-025-03722-1
D. L. Belgin Paul, Praveen Ayyappan Susila, M. Karthick
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Abstract

In recent years, notable advancements have been achieved in the domain of tissue engineering and regenerative medicine, presenting auspicious remedies for the management of diverse injuries and ailments. The management of bone injuries necessitates the implementation of a customized approach depending upon the specific nature of the injury. Tissue engineering plays a major role in the treatment of such bone injuries. One key aspect of tissue engineering is the development of scaffolds that can provide structural support and guide the growth of new tissue. The scaffold should possess mechanical properties that enable it to withstand weight-bearing stresses, resembling the strength and durability of real bone. This review explores the latest research findings from pioneering research papers in tissue engineering, focusing on scaffolds, bioceramics, and the various technique for the development of scaffolds with a focus on 3D printing. By examining and synthesizing key studies in these areas, this review aims to provide insights into the current state of knowledge, identify research gaps, and contribute to the advancement of tissue engineering approaches for regenerative medicine applications.

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探索生物陶瓷支架制造技术,重点是DIW 3D打印在组织工程中的应用。
近年来,组织工程和再生医学领域取得了显著进展,为各种损伤和疾病的治疗提供了吉祥的补救措施。骨损伤的管理需要根据损伤的具体性质实施定制的方法。组织工程在此类骨损伤的治疗中起着重要作用。组织工程的一个关键方面是支架的发展,可以提供结构支持和指导新组织的生长。支架应该具有机械性能,使其能够承受负重压力,类似于真骨的强度和耐久性。本文综述了组织工程领域的最新研究成果,重点介绍了支架、生物陶瓷以及以3D打印为重点的各种支架开发技术。通过对这些领域的关键研究进行梳理和综合,本综述旨在提供对知识现状的见解,找出研究空白,并为再生医学应用的组织工程方法的发展做出贡献。
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来源期刊
Annals of Biomedical Engineering
Annals of Biomedical Engineering 工程技术-工程:生物医学
CiteScore
7.50
自引率
15.80%
发文量
212
审稿时长
3 months
期刊介绍: Annals of Biomedical Engineering is an official journal of the Biomedical Engineering Society, publishing original articles in the major fields of bioengineering and biomedical engineering. The Annals is an interdisciplinary and international journal with the aim to highlight integrated approaches to the solutions of biological and biomedical problems.
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