De Novo Genome Assembly and Comparative Genome Analysis of the Novel Human Fungal Pathogen Trichosporon austroamericanum Type-Strain CBS 17435.

IF 2.9 3区 生物学 Q2 MYCOLOGY Mycopathologia Pub Date : 2025-04-04 DOI:10.1007/s11046-025-00942-w
Elaine C Francisco, Marie Desnos-Ollivier, Bert Gerrits van den Ende, Ferry Hagen
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Abstract

Trichosporon austroamericanum is a recently described species recognized for its emerging clinical significance in invasive trichosporonosis. In this study, we present the nanopore long-read-based de novo genome assembly of the type-strain CBS 17435. Additionally, we performed genomic comparative analyses with its closest relative, Trichosporon inkin.

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新型人类真菌病原体austroamericantrichosporon typestrain CBS 17435的从头基因组组装和比较基因组分析。
美洲毛磷虫是最近发现的一种物种,因其在侵袭性毛磷病中的临床意义而得到认可。在这项研究中,我们提出了基于纳米孔长读基的新型菌株CBS 17435的从头基因组组装。此外,我们进行了基因组比较分析与它最近的亲戚,三磷酸丝氨酸。
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来源期刊
Mycopathologia
Mycopathologia 生物-真菌学
CiteScore
6.80
自引率
3.60%
发文量
76
审稿时长
3 months
期刊介绍: Mycopathologia is an official journal of the International Union of Microbiological Societies (IUMS). Mycopathologia was founded in 1938 with the mission to ‘diffuse the understanding of fungal diseases in man and animals among mycologists’. Many of the milestones discoveries in the field of medical mycology have been communicated through the pages of this journal. Mycopathologia covers a diverse, interdisciplinary range of topics that is unique in breadth and depth. The journal publishes peer-reviewed, original articles highlighting important developments concerning medically important fungi and fungal diseases. The journal highlights important developments in fungal systematics and taxonomy, laboratory diagnosis of fungal infections, antifungal drugs, clinical presentation and treatment, and epidemiology of fungal diseases globally. Timely opinion articles, mini-reviews, and other communications are usually invited at the discretion of the editorial board. Unique case reports highlighting unprecedented progress in the diagnosis and treatment of fungal infections, are published in every issue of the journal. MycopathologiaIMAGE is another regular feature for a brief clinical report of potential interest to a mixed audience of physicians and laboratory scientists. MycopathologiaGENOME is designed for the rapid publication of new genomes of human and animal pathogenic fungi using a checklist-based, standardized format.
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