Rita de Sousa, Francisco Miguel Rodrigues, Carolina Maia, Alice Carvalho, Inês Luz, Gustavo Soares, Ana Margarida Novo, Olinda Rebelo, Stephan Frank, Jürgen Hench, Sílvia Carvalho
{"title":"Olfactory schwannoma in an adolescent: a case report.","authors":"Rita de Sousa, Francisco Miguel Rodrigues, Carolina Maia, Alice Carvalho, Inês Luz, Gustavo Soares, Ana Margarida Novo, Olinda Rebelo, Stephan Frank, Jürgen Hench, Sílvia Carvalho","doi":"10.1007/s00247-025-06227-0","DOIUrl":null,"url":null,"abstract":"<p><p>Olfactory schwannoma is a very rare tumor, whose origin is still under investigation. We report the case of a 16-year-old adolescent who presented with worsening headaches, hyposmia, and a convulsive crisis. Brain imaging showed a frontobasal lesion, attached to the cribriform plate, with solid and multiseptated cystic components. The patient underwent complete resection of the lesion. A comprehensive molecular study confirmed a methylation pattern consistent with schwannoma. Although rare, olfactory schwannomas should be considered in the differential diagnosis of anterior cranial fossa tumors. Given its benign nature, a complete resection leads to favorable long-term outcomes.</p>","PeriodicalId":19755,"journal":{"name":"Pediatric Radiology","volume":" ","pages":"1029-1033"},"PeriodicalIF":2.3000,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12065719/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Pediatric Radiology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s00247-025-06227-0","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/4/5 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"PEDIATRICS","Score":null,"Total":0}
引用次数: 0
Abstract
Olfactory schwannoma is a very rare tumor, whose origin is still under investigation. We report the case of a 16-year-old adolescent who presented with worsening headaches, hyposmia, and a convulsive crisis. Brain imaging showed a frontobasal lesion, attached to the cribriform plate, with solid and multiseptated cystic components. The patient underwent complete resection of the lesion. A comprehensive molecular study confirmed a methylation pattern consistent with schwannoma. Although rare, olfactory schwannomas should be considered in the differential diagnosis of anterior cranial fossa tumors. Given its benign nature, a complete resection leads to favorable long-term outcomes.
期刊介绍：
Official Journal of the European Society of Pediatric Radiology, the Society for Pediatric Radiology and the Asian and Oceanic Society for Pediatric Radiology
Pediatric Radiology informs its readers of new findings and progress in all areas of pediatric imaging and in related fields. This is achieved by a blend of original papers, complemented by reviews that set out the present state of knowledge in a particular area of the specialty or summarize specific topics in which discussion has led to clear conclusions. Advances in technology, methodology, apparatus and auxiliary equipment are presented, and modifications of standard techniques are described.
Manuscripts submitted for publication must contain a statement to the effect that all human studies have been reviewed by the appropriate ethics committee and have therefore been performed in accordance with the ethical standards laid down in an appropriate version of the 1964 Declaration of Helsinki. It should also be stated clearly in the text that all persons gave their informed consent prior to their inclusion in the study. Details that might disclose the identity of the subjects under study should be omitted.
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