Effects of acute and chronic ranitidine administration on renal function and parathyroid activity in chronic renal failure.

N Pozet, M Labeeuw, A Hadj Aissa, C Bizolon, P Zech, J Traeger
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Abstract

In 11 patients with advanced renal failure, chronic treatment with ranitidine decreased plasma immunoreactive parathormone (PTH) without affecting phosphate reabsorption or urinary excretion of cyclic AMP. No significant changes in glomerular filtration rate and in urinary excretion of electrolytes were evident.

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急性和慢性雷尼替丁对慢性肾功能衰竭患者肾功能和甲状旁腺活性的影响。
在11例晚期肾衰竭患者中,雷尼替丁慢性治疗可降低血浆免疫反应性甲状旁腺激素(PTH),但不影响磷酸重吸收或尿中环AMP的排泄。肾小球滤过率和尿中电解质排泄无明显变化。
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