[Use of electrons above 20 MeV for reduction of radiation exposure].

Strahlentherapie Pub Date : 1985-07-01
D Fehrentz, B Kimmig, K zum Winkel, G A Zakaria
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Abstract

After many years of clinical application of a 42 MeV betatron, the following indications were found for deep therapy with electrons above 20 MeV: tumors situated in the brain, mediastinum, kidney, liver, bladder, rectum, as well as peripheral tumors situated in different body regions. For eight different cases, the total body exposure and the radiation exposure of some risk organs was calculated for an irradiation with electrons alone, a combination of electrons and photons, an irradiation with 42 MeV X-rays and with Co-60 gamma rays alone. All these calculations were based on a most favorable irradiation technique. The results showed that electrons up to 40 MeV can spare more than 30% of the total body dose; a combination of electrons and photons allows a reduction of the total dose of about 15% as against that of photons alone, which makes possible a better conservation of skin. This total dose reduction corresponds to that achieved by the substitution of ultrahard X-radiation for Co-60 gamma radiation in deep therapy. The radiation exposure of risk organs can often be reduced by the use of electrons, too. Thus electron deep therapy shows to be justified for the mentioned tumor cases. This is also confirmed by clinical experience.

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[使用20兆电子伏以上的电子以减少辐射暴露]。
经过42兆电子伏特的多年临床应用,发现20兆电子伏特以上电子深度治疗的适应症有:位于脑、纵隔、肾、肝、膀胱、直肠的肿瘤,以及位于身体不同部位的外周肿瘤。在8个不同的病例中,计算了单独电子照射、电子和光子结合照射、42 MeV x射线照射和单独Co-60伽马射线照射的总暴露量和某些危险器官的辐射暴露量。所有这些计算都是基于最有利的辐照技术。结果表明,高达40 MeV的电子可以节省30%以上的人体总剂量;与单独使用光子相比,电子和光子的结合可以使总剂量减少约15%,这使得更好地保护皮肤成为可能。这种总剂量减少相当于在深度治疗中用超硬x射线代替Co-60伽马射线所达到的剂量减少。危险器官的辐射暴露通常也可以通过使用电子来减少。因此,电子深度治疗对上述肿瘤病例是合理的。临床经验也证实了这一点。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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