Serum lipid peroxide levels in rats with inherited cataracts.

Journal of applied biochemistry Pub Date : 1985-06-01
K Yagi, S Komura, N Ihara, H Abe, H Konishi, S Arichi
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Abstract

In a new strain of rat with inherited cataracts, a postnatal increase in serum lipid peroxide level was observed. It reached the maximum on the 13th day after birth. This seems to be a reflection of the increased lipid peroxides in the liver. In accordance with the increase in serum lipid peroxide level, the occurrence of vacuoles in the subcapsular fibers of the posterior region of the lens was observed by electron microscopy, suggesting a relationship between the increase in serum lipid peroxides and the provocation of cataract formation.

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遗传性白内障大鼠血清脂质过氧化水平。
在一种新的遗传性白内障大鼠品系中,观察到出生后血清脂质过氧化水平升高。在出生后第13天达到最大值。这似乎是肝脏中脂质过氧化物增加的反映。根据血清过氧化脂水平的升高,电镜观察到晶状体后区囊下纤维出现空泡,提示血清过氧化脂的升高与诱发白内障的形成有一定的关系。
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