{"title":"[Properties of a low-molecular weight DNA from embryonic rat cells in culture].","authors":"R Manso-Martinez, W Frank","doi":"10.1515/znb-1972-1215","DOIUrl":null,"url":null,"abstract":"Normal embryonic rat cells, which are synchronized in G1 phase of their cell cycle, by incubation in serum-free medium contain a DNA fraction with a sedimentation coefficient S20 between 11 and 12. This double-stranded DNA shows a significantly higher buoyant density in caesiumchloride than does the bulk of cellular DNA, and its replication is not restricted to a distinct part of the S period. The possible role of these DNA subunits in the replication mechanism is discussed","PeriodicalId":78857,"journal":{"name":"Zeitschrift fur Naturforschung. Teil B. Anorganische Chemie, organische Chemie, Biochemie, Biophysik, Biologie","volume":"27 12","pages":"1507-15"},"PeriodicalIF":0.0000,"publicationDate":"1972-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1515/znb-1972-1215","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Zeitschrift fur Naturforschung. Teil B. Anorganische Chemie, organische Chemie, Biochemie, Biophysik, Biologie","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1515/znb-1972-1215","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Normal embryonic rat cells, which are synchronized in G1 phase of their cell cycle, by incubation in serum-free medium contain a DNA fraction with a sedimentation coefficient S20 between 11 and 12. This double-stranded DNA shows a significantly higher buoyant density in caesiumchloride than does the bulk of cellular DNA, and its replication is not restricted to a distinct part of the S period. The possible role of these DNA subunits in the replication mechanism is discussed
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