Spontaneous tumors of the nervous system and associated organs and/or tissues in rats.

Gan Pub Date : 1984-09-01
A Maekawa, H Onodera, H Tanigawa, K Furuta, M Takahashi, Y Kurokawa, T Kokubo, T Ogiu, O Uchida, K Kobayashi
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Abstract

Spontaneous tumors of the nervous system and associated organs and/or tissues in 346 male and 346 female F344/DuCrj rats and 200 male and 177 female Slc:Wistar rats were examined. The main neurogenic tumors observed were gliomas and neurinomas, which were detected in both strains of rats. Out of 7 gliomas, 6 were found in the brain and 1 in the spinal cord, and out of 4 neurinomas, 2 were in the trigeminal nerves and the other 2 were in the spinal nerves. In addition, other types of tumors (2 granular cell tumors in the brain, 1 pinealoma, 3 ganglioneuromas in the adrenal gland, 1 undifferentiated carcinoma in the nasal cavity and 1 chordoma in the posterior neck region) were observed.

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大鼠神经系统及相关器官和/或组织的自发性肿瘤。
对346只雄性和346只雌性F344/DuCrj大鼠以及200只雄性和177只雌性Slc:Wistar大鼠的神经系统及相关器官和/或组织的自发性肿瘤进行了检测。观察到的主要神经源性肿瘤为神经胶质瘤和神经鞘瘤,这两种肿瘤在大鼠中均有发现。7例神经胶质瘤中,6例发生在脑部,1例发生在脊髓;4例神经鞘瘤中,2例发生在三叉神经,2例发生在脊神经。此外,其他类型肿瘤(脑颗粒细胞瘤2例、松果体瘤1例、肾上腺神经节瘤3例、鼻腔未分化癌1例、后颈部脊索瘤1例)。
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