Diclofenac sodium, diflunisal and naproxen: patient preferences for anti-inflammatory drugs in rheumatoid arthritis.

E C Huskisson, P A Dieppe, J Scott, H Jones
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引用次数: 9

Abstract

Ninety patients with active rheumatoid arthritis took part in a cross-over trial comparing diclofenac sodium, diflunisal and naproxen. The efficacy of the three drugs was similar though there were trends in favour of diclofenac sodium in some measurements. The incidence of side-effects was similar with the three drugs and each was chosen by a significant group of patients as continuation therapy at the end of the study.

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双氯芬酸钠、双氟尼拉和萘普生:类风湿关节炎患者对抗炎药物的偏好。
90名活动性类风湿关节炎患者参加了一项比较双氯芬酸钠、双氟尼拉和萘普生的交叉试验。这三种药物的疗效是相似的,尽管在某些测量中有有利于双氯芬酸钠的趋势。副作用的发生率与这三种药物相似,并且在研究结束时,每一种药物都被一组显著的患者选择作为继续治疗。
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A comparison of three ways of measuring pain. A double-blind comparative study of metronidazole and placebo in rheumatoid arthritis. Evaluation of a single daily dose of naproxen in osteoarthritis. Toxic epidermal necrolysis in a patient treated with gold salts and benoxaprofen. A pharmacist's audit of antirheumatic drugs.
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