[The comparative radiosensitivity of the lymphocytes of men and women under gamma irradiation at the G0 stage of the mitotic cycle].

Radiobiologiia Pub Date : 1993-05-01
G M Obaturov, B A Bogatykh
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Abstract

Radiosensitivity of male and female lymphocytes exposed to gamma radiation (60Co) in phase G0 of the mitotic cycle has been comparatively studied. The radiosensitivity was shown to be identical, within the limits of error, although with the recombination repair (the nonhomologous nature of X and Y chromosomes being taken into account) the number of chromosome aberrations in male cells must be 1.4 times larger than in female cells. This indicates an absence or (within the limits of error) an insignificant role of the recombination repair of double-strand DNA breaks.

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[有丝分裂周期G0期γ射线照射下男性和女性淋巴细胞的放射敏感性比较]。
比较研究了有丝分裂周期G0期γ射线(60Co)对男性和女性淋巴细胞的放射敏感性。在误差范围内,放射敏感性被证明是相同的,尽管考虑到重组修复(考虑到X和Y染色体的非同源性),男性细胞中的染色体畸变数量必须是女性细胞的1.4倍。这表明双链DNA断裂的重组修复缺失或(在误差范围内)作用微不足道。
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