{"title":"[The effect of He-Ne laser radiation on the chemiluminescence of human neutrophils].","authors":"I A Shchepetkin, V V Udut, A B Karpov","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>A study was made of the influence of He-Ne laser radiation (lambda = 632.8 nm) on spontaneous chemiluminescence (CL) of human neutrophils as well as its effect on CL stimulated by calcium ionophore (A23187) and protein kinase activator (phorbol-12-myristate-13-acetate, PMA). In vitro irradiation of the blood and a neutrophil suspension activated spontaneous CL and modulated that stimulated by A23187 (1 microM) and PMA (10 nM) within the dose range from 0.01 to 6 J/cm3. The modulation effect of irradiation is a function of radiation dose and the initial value of the integral index of stimulated CL.</p>","PeriodicalId":20808,"journal":{"name":"Radiobiologiia","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"1993-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Radiobiologiia","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
A study was made of the influence of He-Ne laser radiation (lambda = 632.8 nm) on spontaneous chemiluminescence (CL) of human neutrophils as well as its effect on CL stimulated by calcium ionophore (A23187) and protein kinase activator (phorbol-12-myristate-13-acetate, PMA). In vitro irradiation of the blood and a neutrophil suspension activated spontaneous CL and modulated that stimulated by A23187 (1 microM) and PMA (10 nM) within the dose range from 0.01 to 6 J/cm3. The modulation effect of irradiation is a function of radiation dose and the initial value of the integral index of stimulated CL.
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