[Assessment of left ventricular function by pressure-volume loop in VSD and TOF before and after operation].

S Shimizu, H Kurosawa, M Nakano, K Hashimoto, K Suzuki, M Yamagishi, H Okuyama, K Nomura
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Abstract

This study estimates the perioperative left ventricular function of VSD and TOF by using Pressure-Volume (PV) loop. The most characteristic hemodynamic change of VSD is a decreased volume load. Although ejection fraction significantly decreased after the operation, this change did not mean a deteriorated left ventricular contractility. Emax, which is an index of left ventricular contractility on PV loop, improved and pressure-volume area (PVA) which is correlated with 02 consumption of left ventricule was reduced. Mechanical efficiency of left ventricular energetic state did not significantly change. Left ventricular volume and ejection fraction in TOF slightly increased after the operation. Increased ejection fraction reflected a compensation to volume overload after surgery. Emax slightly decreased and PVA increased. Meanwhile mechanical efficiency increased after the operation indicating well preserved ventricular contractility. In particular, the shape of PV loop of both VSD and TOF eventually became usual square after operation due to recover of the isovolumic contraction and relaxation phase. These characteristics had better to be concerned for improvement of surgical techniques as in conotruncal repair, particularly in TOF in the setting of better quality of life with low atrial pressure.

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[术前、术后VSD和TOF左心室功能的压力-容积环评价]。
本研究采用压力-容积(PV)环路评价VSD和TOF围术期左心室功能。室间隔缺损最典型的血流动力学变化是容积负荷降低。虽然术后射血分数明显下降,但这一变化并不意味着左室收缩性恶化。与左室02耗气量相关的压力容积面积(pressure-volume area, PVA)降低。左室能态机械效率无明显变化。术后TOF患者左室容积和射血分数略有升高。射血分数的增加反映了手术后对容量过载的补偿。Emax略有下降,PVA略有上升。同时,手术后机械效率提高,表明心室收缩功能保存良好。特别是VSD和TOF的PV回路,由于等体积收缩弛豫阶段的恢复,手术后PV回路的形状最终变为通常的方形。这些特点最好关注于圆锥截骨修复手术技术的改进,特别是在低心房压、生活质量更好的TOF中。
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