DNA-protein cross-links in different organs of mice induced by the combined action of zinc and gamma-irradiation.
IF 2.3 4区 生物学Q3 BIOCHEMISTRY & MOLECULAR BIOLOGYBiochemistry (Moscow)Pub Date : 1999-02-01
A N Osipov, V D Sypin, G Y Kolomijtseva
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引用次数: 0
Abstract
Fractional whole-body gamma-irradiation of mice at total doses of 0. 5-1.5 Gy induces increased DNA-protein cross-links (DPCs) in thymus, spleen, and brain, whereas in liver no DPCs are detected. Chronic administration of zinc ions in drinking water at concentration 10 mg/liter for 20-30 days increased DPCs in thymus, spleen, brain, and liver of mice. The combined action of zinc ions and gamma-radiation produced a significantly lower amount of DPCs than was induced by the separate action of these agents.
期刊介绍：
Biochemistry (Moscow) is the journal that includes research papers in all fields of biochemistry as well as biochemical aspects of molecular biology, bioorganic chemistry, microbiology, immunology, physiology, and biomedical sciences. Coverage also extends to new experimental methods in biochemistry, theoretical contributions of biochemical importance, reviews of contemporary biochemical topics, and mini-reviews (News in Biochemistry).
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