[Ernst Wertheim, or the significance of the EBM of the cervical cancer].

S Leodolter
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引用次数: 3

Abstract

In the field of gynecologic oncology, the beginning of the 20(th) century was dominated by a dispute between Wertheim and Schauta over the best surgical approach for cervical cancer in general, and the role of lymphonodectomy in particular. Since that time, important progress has been made with respect to diagnosis and therapy. This refers a) to the inclusion of patients with malignant diseases into clinical studies with the subsequent design and development of evidence based therapy strategies and b) on the important role of endoscopic techniques in gynecologic oncology. Some of the controversies of the "Wertheim/Schauta" era such as the "lymph node problem" are not fully resolved to date. The future will be most likely not based on diagnosis and therapy of cervical cancer, but on primary prevention with the introduction of a potent vaccination against HPV, which will be commercially available soon.

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[Ernst Wertheim,或EBM对宫颈癌的意义]。
在妇科肿瘤学领域,20世纪初,Wertheim和Schauta对宫颈癌的最佳手术方式,特别是淋巴切除术的作用的争论占据了主导地位。从那时起,在诊断和治疗方面取得了重要进展。这是指a)将恶性疾病患者纳入临床研究,并随后设计和开发基于证据的治疗策略;b)内镜技术在妇科肿瘤学中的重要作用。“Wertheim/Schauta”时代的一些争议,如“淋巴结问题”,至今仍未完全解决。未来很可能不是基于宫颈癌的诊断和治疗,而是基于初级预防,引入针对HPV的强效疫苗,这种疫苗很快就会上市。
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