New concepts in median nail dystrophy, onychomycosis, and hand, foot, and mouth disease nail pathology.

ISRN Dermatology Pub Date : 2012-01-01 Epub Date: 2012-01-26 DOI:10.5402/2012/680163
Nathan Y Hoy, Alexander K C Leung, Andrei I Metelitsa, Stewart Adams
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引用次数: 34

Abstract

Nails are underutilized as diagnostic tools, despite being involved in many dermatologic conditions. This paper explores new concepts in the treatment of median nail dystrophy (MND), onychomycosis, and the nail pathology of hand, foot, and mouth disease (HFMD). A Pubmed database literature search was conducted for MND treatment, onychomycosis treatment, and HFMD nail pathology. Only papers published after January 2008 were reviewed. The results showed that 0.1% tacrolimus ointment can be an effective treatment for MND. Early studies on laser therapy indicate that it is a safe and efficacious treatment option for onychomycosis, compared to conventional oral antifungal agents. Vicks VapoRub (The Proctor & Gamble Company, Cincinnati, OH) is effective against onychomycosis and is a reasonable option in patients who choose to forgo conventional treatments. Lastly, there is evidence to support a correlation between HFMD and onychomadesis.

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中位甲营养不良、甲真菌病、手足口病指甲病理学的新概念。
指甲被充分利用作为诊断工具,尽管涉及许多皮肤病。本文探讨了中位甲营养不良(MND)、甲真菌病和手足口病(HFMD)的指甲病理治疗的新概念。在Pubmed数据库中检索MND治疗、甲真菌病治疗和手足口病指甲病理的文献。只对2008年1月以后发表的论文进行了审查。结果表明,0.1%他克莫司软膏可有效治疗MND。早期的研究表明,激光治疗是一种安全有效的治疗选择,对于甲真菌病,相比传统的口服抗真菌药物。Vicks VapoRub (The Proctor & Gamble Company, Cincinnati, OH)对甲真菌病有效,对于放弃传统治疗的患者来说是一个合理的选择。最后,有证据支持手足口病和牙根形成之间的相关性。
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