Addictive neurons.

Therapeutic targets for neurological diseases Pub Date : 2017-01-01 Epub Date: 2017-01-30
Sodikdjon A Kodirov
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Abstract

Since the reward center is considered to be the area tegmentalis ventralis of the hypothalamus, logically its neurons could mainly be responsible for addiction. However, the literature asserts that almost any neurons of CNS can respond to one or another addictive compound. Obviously not only addictive nicotine, but also alcohol, amphetamine, cannabis, cocaine, heroin and morphine may influence dopaminergic cells alone in VTA. Moreover, paradoxically some of these drugs ameliorate symptoms, counterbalance syndromes, cure diseases and improve health, not only those related to the CNS and in adults, but also almost all other organs and in children, e.g. epilepsy.

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成瘾性神经元
由于奖赏中枢被认为是下丘脑腹侧被盖区,从逻辑上讲,它的神经元可能是导致成瘾的主要原因。然而,文献断言,几乎所有中枢神经系统的神经元都能对一种或另一种成瘾化合物做出反应。显然,不仅是尼古丁会上瘾,酒精、苯丙胺、大麻、可卡因、海洛因和吗啡也会影响 VTA 中的多巴胺能细胞。此外,令人费解的是,其中一些药物还能改善症状、消除综合症、治疗疾病和改善健康状况,不仅是与中枢神经系统有关的药物和成人药物,还包括几乎所有其他器官的药物和儿童药物,例如癫痫。
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