Clinical management of osteoporotic vertebral fracture treated with percutaneous vertebroplasty.

Q3 Medicine Clinical Cases in Mineral and Bone Metabolism Pub Date : 2017-05-01 Epub Date: 2017-10-25 DOI:10.11138/ccmbm/2017.14.1.161
Anna Capozzi, Giovanni Scambia, Alessandro Pedicelli, Maurizio Evangelista, Roberto Sorge, Stefano Lello
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Abstract

Our study demonstrated percutaneous vertebroplasty (PVP) is an effective procedure to rapidly reduce back pain in patients affected by acute osteoporotic vertebral compression fractures (OVCFs) assessed by MRI. We confirmed in our sample, femoral bone density impacts more deeply than vertebral T-score and/or BMD on bone strenght, as it is less affected by any interferences. We interestingly found the presence of previous osteoporotic fragility fractures and chronic glucocorticoids therapy should especially negatively influence bone health of our patients. On the other hand, even if both FRAX scores for major osteoporotic fractures and for femoral fractures seemed to globally define a population at major risk for fragility fractures, our analysis is retrospectively done. We choose and suggest a multidisciplinary medical management of these patients, considering OP is a multifactorial disease and OVCFs usually produce lots of different important consequences on general health.

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经皮椎体成形术治疗骨质疏松性脊椎骨折的临床管理。
我们的研究表明,经皮椎体成形术(PVP)是一种有效的治疗方法,可迅速减轻经磁共振成像评估的急性骨质疏松性椎体压缩骨折(OVCF)患者的背痛。我们在样本中证实,股骨骨密度比椎体 T 评分和/或 BMD 对骨强度的影响更深,因为它受任何干扰因素的影响较小。有趣的是,我们发现既往有骨质疏松性脆性骨折和长期糖皮质激素治疗的患者尤其会对骨健康产生负面影响。另一方面,即使主要骨质疏松性骨折和股骨骨折的 FRAX 评分似乎能全面界定脆性骨折的高危人群,但我们的分析是回顾性的。考虑到骨质疏松症是一种多因素疾病,而脆性骨折通常会对全身健康产生许多不同的重要影响,我们选择并建议对这些患者进行多学科医疗管理。
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来源期刊
Clinical Cases in Mineral and Bone Metabolism
Clinical Cases in Mineral and Bone Metabolism ENDOCRINOLOGY & METABOLISM-
CiteScore
2.60
自引率
0.00%
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0
期刊介绍: The Journal encourages the submission of case reports and clinical vignettes that provide new and exciting insights into the pathophysiology and characteristics of disorders related to skeletal function and mineral metabolism and/or highlight pratical diagnostic and /or therapeutic considerations.
期刊最新文献
From the Editor-in-Chief. Hypothyrodism as a risk factor of periodontitis and its relation with vitamin D deficiency: mini-review of literature and a case report. Atypical femur fractures: a distinctive tract of adult hypophosphatasia. Surgical treatment of neglected hip fracture in children with cerebral palsy: case report and review of the literature. Pitfalls in interpreting interventional studies for osteoporosis.
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