Mastication as a tool to prevent cognitive dysfunctions

IF 5.7 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Japanese Dental Science Review Pub Date : 2018-11-01 DOI:10.1016/j.jdsr.2018.06.001
Gayathri Krishnamoorthy, Aparna I. Narayana, Dhanasekar Balkrishanan
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引用次数: 24

Abstract

Mastication as we all know has always been related to its primary function of digestion, but little do we know that it produces an enhancing effect on general health, especially the cognitive performance related aspects of memory. Recent studies have shown its association with activation of various brain regions, however little is known about its effects on neuronal activity in these specified regions. According to the enormous evidences collected so far, mastication has proved to be effective in conducting huge amount of sensory information to the brain, and maintaining learning and memory functions of hippocampus. Therefore it is essential that we maintain normal occlusion and preserve the masticatory function as long as possible to prevent the attenuation of hippocampus, caused by occlusal disharmony and reduced mastication. We provide an overview on how mastication activates various cortical areas of the brain and how an increase in the cerebral blood oxygen level of hippocampus and prefrontal cortex (PFC) accentuates the learning and memory process. We also justify why maintaining and establishing a normal occlusion is important from neurological point of view.

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咀嚼是预防认知功能障碍的一种工具
我们都知道,咀嚼一直与消化的主要功能有关,但我们很少知道它对一般健康有增强作用,尤其是与记忆有关的认知表现。最近的研究表明,它与大脑各个区域的激活有关,然而,它对这些特定区域的神经元活动的影响知之甚少。根据目前收集到的大量证据,咀嚼被证明可以有效地向大脑传递大量的感觉信息,维持海马的学习和记忆功能。因此,维持正常咬合,尽可能长时间地保持咀嚼功能,防止因咬合不协调而导致海马的衰减,减少咀嚼是至关重要的。我们概述了咀嚼如何激活大脑皮层的各个区域,以及海马和前额叶皮质(PFC)脑血氧水平的增加如何加强学习和记忆过程。我们也证明为什么维持和建立一个正常的闭塞是重要的从神经学的观点。
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来源期刊
Japanese Dental Science Review
Japanese Dental Science Review DENTISTRY, ORAL SURGERY & MEDICINE-
CiteScore
9.90
自引率
1.50%
发文量
31
审稿时长
32 days
期刊介绍: The Japanese Dental Science Review is published by the Japanese Association for Dental Science aiming to introduce the modern aspects of the dental basic and clinical sciences in Japan, and to share and discuss the update information with foreign researchers and dentists for further development of dentistry. In principle, papers are written and submitted on the invitation of one of the Editors, although the Editors would be glad to receive suggestions. Proposals for review articles should be sent by the authors to one of the Editors by e-mail. All submitted papers are subject to the peer- refereeing process.
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