Small cell glioblastoma multiforme: a case series and clinicopathological update.

Q1 Medicine CNS Oncology Pub Date : 2020-12-01 Epub Date: 2020-12-07 DOI:10.2217/cns-2020-0016
Arun Kumar Yadav, Renu Madan, Debajyoti Chatterjee, Shalin Dhiman, Shikha Goyal, Narendra Kumar, Sushanta Kumar Sahoo
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引用次数: 1

Abstract

Small cell glioblastoma (scGBM) is a rare histological variant of classical glioblastoma (GBM). Presence of necrosis and microvascular proliferation is not essential for the diagnosis. It is thought to have more aggressive behavior as compared with classical GBM; however, because of its rarity standard treatment guidelines are not available. Adjuvant treatment for these cancers consists of postoperative radiotherapy with concurrent and maintenance temozolomide similar to classical GBM. Here we present a case series of five small cell glioblastoma patients along with the clinical-pathological review.

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多形性小细胞胶质母细胞瘤:病例系列和临床病理进展。
小细胞胶质母细胞瘤(scGBM)是典型胶质母细胞瘤(GBM)的一种罕见的组织学变异。坏死和微血管增生的存在并不是诊断的必要条件。与经典GBM相比,它被认为具有更强的攻击性行为;然而,由于其罕见性,尚无标准治疗指南。这些癌症的辅助治疗包括与经典GBM类似的术后放疗同时和维持替莫唑胺。在此,我们报告5例小细胞胶质母细胞瘤患者的临床病理资料。
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来源期刊
CNS Oncology
CNS Oncology Medicine-Neurology (clinical)
CiteScore
3.80
自引率
0.00%
发文量
12
审稿时长
13 weeks
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