Rocuronium-Induced Dilated Nonreactive Pupils in a Patient With Coronavirus Disease 2019: A Case Report.

IF 0.5 A&A Practice Pub Date : 2021-06-24 DOI:10.1213/XAA.0000000000001491
Elba da Paixão Rodrigues, Gustavo Caniné da Costa, Douglas Quintanilha Braga, Jorge Eduardo da Silva Soares Pinto, Marcos Adriano Lessa
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引用次数: 2

Abstract

We report the clinical case of a patient with coronavirus disease 2019 (COVID-19) who had recently undergone neurosurgery and presented with dilated nonreactive pupils during continuous rocuronium infusion, which was reversible with the suspension of the drug. Both the neurosurgical procedure and possible disruption of the blood-brain barrier due to COVID-19 infection may have led to the action of rocuronium in the central nervous system (CNS). Thus, clinicians must remember that neuromuscular blocking agents (NMBAs) can cause dilated nonreactive pupils in patients with COVID-19.

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2019冠状病毒病患者罗库溴铵诱导的无反应性瞳孔扩大1例报告
我们报告了一例2019冠状病毒病(COVID-19)患者的临床病例,该患者最近接受了神经外科手术,在持续输注罗库溴铵时出现无反应性瞳孔扩大,停药后瞳孔可逆。神经外科手术和COVID-19感染可能导致的血脑屏障破坏都可能导致罗库溴铵在中枢神经系统(CNS)中的作用。因此,临床医生必须记住,神经肌肉阻滞剂(nmba)可导致COVID-19患者的无反应性瞳孔扩大。
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A&A Practice
A&A Practice ANESTHESIOLOGY-
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期刊介绍: A & A Case Reports, our new online journal publishing Case Reports, related Editorial Commentary, and Correspondence. Anesthesia & Analgesia 1 and Anesthesiology 2 recently announced that they were suspending publication of Case Reports. One reason is that Case Reports typically reduce the Impact Factor of a journal because they are rarely cited. Regardless of the merits of Impact Factor as a metric of journal worth, journals and their editors necessarily consider Impact Factor in strategic planning. At the same time, Case Reports are appreciated by readers for describing “real life” management of difficult or unusual cases not often encountered by practitioners. In a recent issue of Anesthesia & Analgesia, Steven Shafer1 identified many Case Reports whose publication launched productive careers dedicated to solving the puzzle posed by an unusual observation in a single patient.
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