The Genes Involved in Dentinogenesis.

IF 1.6 4区 生物学 Q4 BIOCHEMISTRY & MOLECULAR BIOLOGY Organogenesis Pub Date : 2022-12-31 Epub Date: 2022-01-13 DOI:10.1080/15476278.2021.2022373
Shuang Chen, Han Xie, Shouliang Zhao, Shuai Wang, Xiaoling Wei, Shangfeng Liu
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引用次数: 6

Abstract

The development and repair of dentin are strictly regulated by hundreds of genes. Abnormal dentin development is directly caused by gene mutations and dysregulation. Understanding and mastering this signal network is of great significance to the study of tooth development, tissue regeneration, aging, and repair and the treatment of dental diseases. It is necessary to understand the formation and repair mechanism of dentin in order to better treat the dentin lesions caused by various abnormal properties, whether it is to explore the reasons for the formation of dentin defects or to develop clinical drugs to strengthen the method of repairing dentin. Molecular biology of genes related to dentin development and repair are the most important basis for future research.

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与牙本质形成有关的基因。
牙本质的发育和修复受到数百个基因的严格调控。牙本质发育异常是由基因突变和失调直接引起的。了解和掌握这一信号网络对研究牙齿发育、组织再生、衰老、修复及牙病的治疗具有重要意义。无论是探究牙本质缺陷形成的原因,还是研发临床药物加强修复牙本质的方法,了解牙本质的形成和修复机制,才能更好地治疗因各种异常性质引起的牙本质病变。牙本质发育与修复相关基因的分子生物学研究是今后牙本质发育与修复研究的重要基础。
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来源期刊
Organogenesis
Organogenesis BIOCHEMISTRY & MOLECULAR BIOLOGY-DEVELOPMENTAL BIOLOGY
CiteScore
4.10
自引率
4.30%
发文量
6
审稿时长
>12 weeks
期刊介绍: Organogenesis is a peer-reviewed journal, available in print and online, that publishes significant advances on all aspects of organ development. The journal covers organogenesis in all multi-cellular organisms and also includes research into tissue engineering, artificial organs and organ substitutes. The overriding criteria for publication in Organogenesis are originality, scientific merit and general interest. The audience of the journal consists primarily of researchers and advanced students of anatomy, developmental biology and tissue engineering. The emphasis of the journal is on experimental papers (full-length and brief communications), but it will also publish reviews, hypotheses and commentaries. The Editors encourage the submission of addenda, which are essentially auto-commentaries on significant research recently published elsewhere with additional insights, new interpretations or speculations on a relevant topic. If you have interesting data or an original hypothesis about organ development or artificial organs, please send a pre-submission inquiry to the Editor-in-Chief. You will normally receive a reply within days. All manuscripts will be subjected to peer review, and accepted manuscripts will be posted to the electronic site of the journal immediately and will appear in print at the earliest opportunity thereafter.
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