A case of complex multisite carbapenem-resistant Klebsiella pneumoniae infection and literature analysis

Abstract

Objective： To analyze a case of complex multisite carbapenems-resistant Klebsiella pneumoniae（CRKP） infection，and to evaluate the rationality of the treatment scheme，so as to provide reference for rational use of drugs.Methods：The clinical and laboratory data of the patient were collected，and the clinical efficacy was observed，laboratory indexes and the results of etiological examination were compared，treatment effect was evaluated and relevant literature was reviewed.Results and Conclusion： In the treatment of the patient，meropenem，amikacin combined with fosfomycin were used.Literature retrieval revealed that there were many kinds of antimicrobial therapy options for CRKP infection，but cure rate was not clear.The prevalence of CRKP was more feasible in the intensive care unit（ICU）.Reducing irrational use of broad-spectrum antibacterials and unnecessary invasive manipulation were effective strategies for the control of CRKP prevalence and reduction of economic burden on patients.